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Emergency services have rushed four children to hospital following a house fire in Birmingham which police suspect may be an arson attack.
The girls, aged four, eight, 10, and 12, were rescued as the blaze tore through the house in the Erdington area of the city.
West Midlands Police say a 37-year-old man has been arrested on suspicion of attempted murder following the fire.
A 29-year-old woman has also been arrested on suspicion of child neglect.
The children were all treated for smoke inhalation at hospital, where their conditions are unknown.
Emergency services were called after flames were seen leaping from the property at around 2.30am Friday morning.
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A total of five people were rescued from the home and West Midlands Ambulance Service said paramedics had treated four girls for the effects of smoke inhalation.
They are receiving further treatment at Birmingham Children's Hospital, the spokesperson said.
West Midlands Fire Service said 20 firefighters had tackled the blaze, which totally destroyed the property.
MailOnline reports that the fire service has confirmed the cause of the fire was arson.
West Midlands Police has now launched an investigation.
The force said: "A 37-year-old man has been arrested on suspicion of attempted murder while a 29-year-old woman has been arrested on suspicion of child neglect. Both remain in police custody.
"A car has also been recovered after it hit a stationary fire engine that was attending the house fire.
"The house has been cordoned off whilst emergency services examine the scene to establish the cause of the fire."
A spokesperson for the fire service said: "We have had four fire engines and 20 firefighters dealing with a severe house fire in Erdington.
"The house has been totally destroyed by fire and we are currently investigating the cause. Five people have been rescued."
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